Saccharine

MOLECULAR FORMULA :-  C7H5NO3S

MOLECULAR WEIGHT :- 183.2 g/mol

SPECIFICATION IP BP USP
Description White crystals or a white, Crystalline powder; Odourless or with a faint, aromatic odour. White or almost white, crystalline powder or colorless crystals. White or almost white, crystalline powder or colorless crystals.
Solubility Sparingly soluble in boiling water and in ethanol (96 %), slightly soluble in cold water. It dissolves in dilute solutions of alkali hydroxides and carbonates
Identification

A.   Reaction

B.    Melting point

C.   IR

D.    Color

E.   color

 

 

 

 

A. Must comply with the saccharin RS

B. An intense green fluorescence develops

C. A violet color develops

D.A saturated solution is acidic to litmus paper.

 

A. a saturated solution, prepared without heating, turns blue litmus paper.

B. 226 °C to 230 °C

C. Must comply with the saccharin RS

D An intense green fluorescence develops.

E. A violet color develops

A: Must comply with the saccharin RS

B:226 °C to 230 °C

 

 

 

 

 

Appearance of solution Solution is Clear & Colorless Solution is Clear & Colorless The test solution shows the same clarity as that of water.
(Relative Substances)

o– and p-Toluene sulfonamide

NMT 10 ppm NMT 10 ppm NMT 10 ppm
Readily carbonisable substances  The solution is not more intensely coloured than reference solution BYS6. The solution is not more intensely coloured than a solution prepared by mixing 0.1 mL of red primary solution, 0.1 mL of blue primary solution and 0.4 mL of yellow primary solution with 4.4 mL of water The solution has no more colour than matching fluid A.
Arsenic NMT 2 ppm  
Heavy metals NMT 2 ppm NMT 10 ppm
Sulphated Ash NMT 0.1 % NMT 0.2 %
Limit of benzoate and salicylate No precipitate or violet color appears in the liquid.
Organic volatile impurities Meets the requirement.
Loss on drying NMT 1.0 % NMT 1.0 % NMT 1.0 %
Assay (dried basis) 98.0 %-101.0 % 99.0 %-101.0 % 99.0 %-101.0 %