Disodium Edetate

MOLECULAR FORMULA :- C10H14N2Na2O82H2O

MOLECULAR WEIGHT :- 372.24 g/ mol

SPECIFICATION IP BP USP
Description A white ,crystalline powder, Odourless White or almost white, crystalline powder. White or almost white, crystalline powder.
Solubility Soluble in water, practically insoluble in ethanol (96 %)
Identification

A.   IR

B.   Reaction

C.   Reaction

D.   Reaction

 

 

 

 

 

A.   Must comply with the disodium edetate RS

B.   No precipitate is produced.

C.   No precipitate is produced.

D.   It gives reaction of sodium salt.

 

 

 

A.   Must comply with the disodium edetate RS

B.   No precipitate is produced.

C.   No precipitate is produced.

D.   It gives reaction of sodium salt.

 

A.   Must comply with the disodium edetate RS

B.   The red color is discharge, leaving a yellowish solution

C.   It gives reaction of sodium salt.

Appearance of solution

 

5 % w/v solution in carbon dioxide free water is Clear & colorless Clear & colorless
pH 4.0-5.5  ( 5  % w/v  solution ) 4.0-5.5 ( 5  % w/v  solution ) 4.0-6.0
Loss on Drying 8.7 %-11.4 %
Calcium No precipitate is formed.
Impurity A

Limit of nitrilotriacetic acid(USP)

NMT 0.1 % NMT 0.1 % NMT 0.1 %
Heavy metals NMT 20 ppm NMT 50 ppm
Iron NMT 80 ppm NMT 80 ppm
Assay 98.5 %-101.0 % 98.5 %-101.0 % 99.0  %-101.0 %(on Dried basis)